Create a database named database_name and enter your root database password
mysql -u root -p -e "CREATE DATABASE database_name CHARACTER SET utf8mb4 COLLATE utf8mb4_unicode_ci";

Create a Drupal site directory. For this setup, websites are at /var/www/
cd /var/www

chown -R www-data:www-data /path/to/folder/

Note that this is a personal workflow of mine and not a tutorial.  Commands may vary according to your setup.